Medical Department Publication List

Medical Department
Publication List

2007 (under review)

Moon SH, Christopher M. Jenkins CM, Mancuso DJ, Turk J, & Gross RW. Arachidonic acid release induced by thapsigargin or ionophore is ablated in aortic smooth muscle cells from mice null for calcium-independent phospholipase A2β, Attenuation of smooth muscle cell migration and proliferation in iPLA2β-null mice. J. Biol. Chem., under revision after review (2007).
Nikolic DM, Gong MC, Turk J, & Post SR. SR-A-mediated macrophage adhesion requires coupling of iPLA2 and 12/15-lipoxygenase to RAC activation. J. Biol. Chem., under revision after review (2007).
Nodari F, Hsu FF, Kao LF, Fu X, Holekamp TF, Crowley JR, Turk J & Holy TE. Identification of a large class of compounds that activate pheromone-sensing neurons. Cell, revision under review (2007).
Ramanadham S, Yarasheski KE, Silva MJ, Wohltmann M, Veis-Novack D, Lei XY, & Turk J. Age-related changes in bone morphology are accelerated in group VIA calcium-independent Phospholipase A2β (iPLA2β)-null mice. Am. J. Pathol., second revision under review (2007).

2007 (published):

Armbrecht HJ, Lakshmi VM, Wickstra J, Hsu FF, & Zenser TV. Metabolism of a heterocyclic amine colon carcinogen in young and old rats. Drug Metab. Dispos. 35: 633-9 (2007).
Bao S, Li Y, Lei X, Wohltmann M, Bohrer A, Jin W, Ramanadham S, Tabas I, & Turk J. Attenuated free cholesterol loading-induced apoptosis and preserved phospholipid composition of peritoneal macrophages from mice that do not express Group VIA Phospholipase A2. J. Biol. Chem. 2007; 282: JBC Papers In Press, doi:10.1074/jbc.M701316200, 07/12/07.
Bateman RJ, Munsell LY, Chen X, Holtzman DM, & Yarasheski KE. Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates. J. Am. Soc. Mass Spectrom. 18: 997-1006 (2007).
Brahmbhatt VV, Hsu FF, Kao JL, Frank EC, & Ford DA. Novel carbonyl and nitrile products from reactive chlorinating species attack of lysosphingolipid. Chem. Phys. Lipids 145: 72-84 (2007).
Cade WT, Reeds DN, Mittendorfer B, Patterson BW, Powderly WG, Klein S, & Yarasheski KE. Blunted lipolysis and fatty acid oxidation during moderate exercise in HIV-infected subjects taking HAART. Am. J. Physiol. Endocrinol. Metab. 292: E812-9 (2007).
Dietzen DJ, Page KL, Tetzloff TA, Bohrer A, & Turk J. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase blunts factor VIIa/tissue factor and prothrombinase activities via effects on membrane phosphatidylserine. Arterioscler Thromb Vasc Biol. 27: 690-6 (2007).
*Hsu FF, Turk J, Owens RM, Rhoades ER, Russell DG. Structural characterization of phosphatidyl-myo-inositol mannosides from Mycobacterium bovis Bacillus Calmette Guerin by multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization. I . PIMs and Lyso-PIMs. J. Am. Soc. Mass Spectrom. 2007;18: 466-478.
*Hsu FF, Turk J, Williams TD, & Welti R. Characterization of phosphatidylglycerol in plant chloroplasts by multiple stage quadrupole ion-trap and tandem quadrupole mass spectrometry with electrospray ionization. J. Am. Soc. Mass Spectrom. 2007;18:783-790.
Hsu FF, Turk J, Zhang K, & Beverley SM. Characterization of inositol phosphorylceramides from Leishmania major by tandem mass spectrometry with electrospray ionization. J. Am. Soc. Mass Spectrom. 18: 1591-604 (2007).
Jacobson DA, Webber C, Bao S, Turk J, & Philipson LH. Modulation of the pancreatic islet beta cell delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate. J. Biol. Chem. 282:7442-7449 (2007).
Lei X, Zhang S, Bohrer A, Bao S, Song H, & Ramanadham S. The Group VIA calcium-independent Phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase. Biochemistry 46: 10170-85 (2007).
Markaverich BM, Alejandro M, Thompson T, Mani S, Reyna A, Portillo W, Sharp J, Turk J, & Crowley J. Tetrahydrofurandiols, leukotoxindiols, and endocrine disruption in rats. Environ. Health Perspect. 115:702-8 (2007).
Mutimura E, Cade WT, Yarasheski KE, Stewart A, & Crowther NJ. Exercise training reduces central adiposity and improves metabolic indices in HAART-treated HIV-positive subjects in Rwanda: a randomized controlled trial. AIDS Res. Human Retrovir., in press (2007).
Okusanya O, Forrest A, DiFrancesco R, Bilic S, Rosenkranz S, Para MF, Adams E, Yarasheski KE, Reichman RC, & Morse GD; ACTG 5043 Protocol Team. Compartmental pharmacokinetic analysis of oral amprenavir with secondary peaks. Antimicrob. Agents Chemother. 51: 1822-6 (2007).
Ostlund RE Jr. Phytosterols, cholesterol absorption and healthy diets. Lipids 42: 41-5 (2007).
Rosch JW, Hsu FF, & Caparon MG. Anionic lipids enriched at the ExPortal of Streptococcus pyogenes. 189: 801-6 (2007).
*Song H, Hsu FF, Ladenson J, & Turk J. Algorithm for processing raw electronic mass spectrometric data to identify and quantitate complex lipid molecular species. J. Am. Soc. Mass Spectrom., Articles in Press, available online 07/29/07.
Thalacker-Mercer AE, Johnson CA, Yarasheski KE, Carnell NS, & Campbell WW. Nutrient ingestion, protein intake, and sex, but not age, affect the albumin synthesis rate in humans. J. Nutr. 137: 1734-40 (2007).
Xie Z, Gong MC, Su W, Turk J, & Guo Z. Group VIA phospholipase A2 (iPLA2b) participates in angiotensin II-induced transcriptional upregulation of RGS2 in vascular smooth muscle cells. J. Biol. Chem. 2007; 282: 25278-89.
Zhang K, Pompey JM, Hsu FF, Turk J, & Beverley SM. Remodeling of sphingolipid metabolism towards de novo synthesis of ethanolamine in Leishmania. EMBO J. 2007;26:1094-1104.

2006:

Baillargeon JP, Diamanti-Kandarakis E, Ostlund RE Jr, Apridonidze T, Iuorno MJ, & Nestler JE. Altered D-chiro-inositol urinary clearance in polycystic ovary syndrome. Diabetes Care 29: 300-5 (2006).
Bao S, Bohrer A, Ramanadham S, Jin W, Zhang S, & Turk J. Effects of stable suppression of Group VIA Phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells. J. Biol. Chem. 281: 187-198 (2006).
Bao S, Song H, Wohltmann M, Bohrer A, & Turk J. Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA Phospholipase A2 and effects of metabolic stress on glucose homeostasis. J. Biol. Chem. 281: 20958-20973 (2006).
Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, & Holtzman DM. Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nat. Med. 12:856-861 (2006).
Cade WT & Yarasheski KE. Metabolic and molecular aspects of sarcopenia. Principles of Molecular Medicine, 2nd Ed. MS Runge and WC Patterson (editors). Humana Press, Inc,, Totowa, NJ, pp. 529-534, (2006).
Goldberg AC, Ostlund RE Jr, Bateman JH, Schimmoeller L, McPherson TB, & Spilburg CA. Effect of plant stanol tablets on low-density lipoprotein cholesterol lowering in patients on statin drugs. Am. J. Cardiol. 97: 376-9 (2006).
*Hsu FF & Turk J. Tandem quadrupole mass spectrometry of sphingomyelin. In The Encyclopedia of Mass Spectrometry. Volume 3: Biological Applications, Part B. Carbohydrates, Nucleic Acids, and Other Biological Compounds (Caprioli R & Gross ML, eds.), pp. 430-437, Elsevier Ltd., Oxford, UK (2006).
**Hsu FF & Turk J. Tandem quadrupole mass spectrometry of sulfatides. In The Encyclopedia of Mass Spectrometry. Volume 3: Biological Applications, Part B. Carbohydrates, Nucleic Acids, and Other Biological Compounds (Caprioli R & Gross ML, eds.), pp. 473-492, Elsevier Ltd., Oxford, UK (2006).
*Hsu FF & Turk J. Characterization of cardiolipin by electrospray ionization with multiple stage quadrupole ion-trap mass spectrometric analysis of [M-2H+Na]- ions. J. Am. Soc. Mass Spectrom 17: 420-42 (2006).
*Hsu FF & Turk J. Characterization of cardiolipin sodiated adducts by positive-ion electrospray ionization with multiple stage quadrupole ion-trap mass spectrometry. J. Am. Soc. Mass Spectrom. 17: 1146-57 (2006).
Ladenson RC, Crimmins DL, Landt Y, & Ladenson JH. Isolation and characterization of a thermally stable recombinant anti-caffeine heavy-chain antibody fragment. Anal. Chem. 78: 4501-8 (2006).
Lakshmi VM, Hsu FF, Schut HA, Zenser TV. Stability and reactivity of 2-nitrosoamino-3,8-dimethylimidazo[4,5-f]quinoxaline. Chem. Res. Toxicol. 19:325-33 (2006).
Lin X, Chen Z, Yue P, Averna MR, Ostlund RE Jr, Watson MA, Schonfeld G. A targeted apoB38.9 mutation in mice is associated with reduced hepatic cholesterol synthesis and enhanced lipid peroxidation. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G1170-6 (2006).
Manary MJ, Muglia LJ, Vogt SK, & Yarasheski KE. Cortisol and its action on the glucocorticoid receptor in malnutrition and acute infection. Metabolism 55:550-4 (2006).
Messner MC, Albert CJ, Hsu FF, & Ford DA. Selective plasmenylcholine oxidation by hypochlorous acid: formation of lysophosphatidylcholine chlorohydrins. Chem. Phys. Lipids. 144: 34-44 (2006).
Nishino K, Hsu FF, Turk J, Cromie MJ, Wösten MMSM, & Groisman EA. Identification of lipopolysaccharide modifications. Molecular Microbiology 61: 645-654 (2006).
Ostlund RE Jr, Lin X. Regulation of cholesterol absorption by phytosterols. Curr. Atheroscler. Rep. 8: 487-91 (2006).
Owens RM, Hsu FF, VanderVen BC, Purdy GE, Hesteande E, Giannakas P, Sacchettini JC, McKinney JD, Hill PJ, Belisle JT, Butcher BA, Pethe K, & Russell DG. A diacylglycerol kinase involved in the biosynthesis of phosphatidylinositol mannosides (PIMs). Mol. Microbiol. 60:1152-63 (2006).
Reeds DN, Cade WT, Patterson BW, Powderly WG, Klein S, Yarasheski KE. Whole body proteolysis rate is elevated in HIV-associated insulin resistance. Diabetes 55: 2849-2855 (2006).
Reeds DN, Yarasheski KE, Fontana L, Cade WT, Laciny E, DeMoss A, Patterson BW, Powderly WG, & Klein S. Alterations in liver, muscle, and adipose tissue insulin sensitivity in men with HIV infection and dyslipidemia. Am. J. Physiol. Endocrinol. Metab. 290:E47-E53 (2006).
Semenkovich CF. Insulin resistance and atherosclerosis. J. Clin. Invest. 116:1813-22 (2006).
Shoulars K, Rodriguez MA, Crowley J, Turk J, Thompson T, & Markaverich BM. Reconstitution of the type II [3H]estradiol binding site with recombinant histone H4. J Steroid Biochem. Mol. Biol. 99:1-8 (2006).
Song H, Ramanadham S, Bao S, Hsu FF, & Turk J. A bromoenol lactone suicide substrate inactivates Group VIA Phospholipase A2 by generating a diffusible bromomethyl ketoacid that alkylates cysteine thiols. Biochemistry 45: 1061-73 (2006).
Song H, Bao S, Ramanadham S, & Turk J. Effects of biological oxidants on the catalytic activity and structure of Group VIA Phospholipase A2. Biochemistry 45: 6392-6404 (2006).
Subramanian S, Derosa MA, Bernal-Mizrachi C, Laffely N, Cade WT, Yarasheski KE, Cryer PE, Semenkovich CF. PPARa activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans. Am J Physiol Endocrinol Metab. 291: E1365-E1371 (2006).
Turk J, Bao S, & Ramanadham S. Lipid messengers from a phospholipase A2 enzyme and beta cell biology. In Commentaries on Perspectives in Diabetes, Volume 2 (1993-1997) (Robertson RP, ed.), pp. 10-20, American Diabetes Association, Alexandria, VA (2006).
Westover EJ, Lin X, Riehl TE, Ma L, Stenson WF, Covey DF, & Ostlund RE Jr. Rapid transient absorption and biliary secretion of enantiomeric cholesterol in hamsters. J. Lipid Res. 47: 2374-81 (2006).
Wildsmith KR, Albert CJ, Hsu FF, Kao JL, & Ford DA. Myeloperoxidase-derived 2-chlorohexadecanal forms Schiff bases with primary amines of ethanolamine glycerophospholipids and lysine. Chem. Phys. Lipids 139:157-70 (2006).
Yan P, Hu XY, Song HW, Yin KJ, Bateman R, Cirrito JR, Xiao QL, Hsu FF, Turk J, Xu J, Hsu CY, Holtzman DM, & Lee JM. Matrix metalloproteinase-9 degrades amyloid beta fibrils in vitro and compact plaques in situ. J. Biol. Chem. 281: 24566-24574 (2006).
*Yarasheski KE, Smith S, & Berger R. Isotope ratio mass spectrometry in human biology: Amino acid metabolism and kinetics. In: The Encyclopedia of Mass Spectrometry (R. Caprioli and M. Gross, eds.), pp. 367-377, Elsevier Publ., New York, NY (2006).
Yin KY, Cirrito JR, Yan P, Hu X, Xiao Q, Pan X, Bateman R, Song H, Hsu FF, Turk J, Xu J, Hsu CY, Mills JC, Holtzman DM, & Lee JM. Matrix metalloproteinases expressed by astrocytes mediate extracellular Aß catabolism. J. Neuroscience 26: 10939-48 (2006).

2005:

Bhasin S, Woodhouse L, Casaburi R, Singh AB, Mac RP, Lee M, Yarasheski KE, Sinha-Hikim I, Dzekov C, Dzekov J, Magliano L, & Storer TW. Older men are as responsive as young men to anabolic effects on skeletal muscle. J Clin Endocrinol Metab. 90: 678-88 (2005).
Binder EF, Yarasheski KE, Steger-May K, Sinacore DR, Brown M, Schechtman KB, & Holloszy JO. Effects of progressive resistance training on body composition in frail older adults. J Gerontol A Biol. Sci. Med. Sci. 60: 1425-31 (2005).
Bohlin K, Patterson BW, Spence KL, Merchak A, Zozobrado JC, Zimmermann LJ, Carnielli VP, & Hamvas A. Metabolic kinetics of pulmonary surfactant in newborn infants using endogenous stable isotope techniques. J Lipid Res. 46:1257-65 (2005).
Carpentier AC, Frisch F, Cyr D, Genereux P, Patterson BW, Giguere R, Baillargeon JP. On the suppression of plasma nonesterified fatty acids by insulin during enhanced intravascular lipolysis in humans. Am. J. Physiol. Endo. Metab. 289: E849-E856, 2005.
Carpentier AC, Patterson BW, Uffelman KD, Salit I, Lewis GF. Mechanism of highly active anti-retroviral therapy-induced hyperlipidemia in HIV-infected individuals. Artherosclerosis. 178: 165-172, 2005.
Chakravarthy MV, Pan Z, Zhu Y, Tordjman K, Schneider J, Coleman T, Turk J, & Semenkovich CF. New hepatic fat activates PPARa to maintain glucose, lipid, and cholesterol homeostasis.Cell Metabolism 1: 309-322 (2005).
Chaparro J, Reeds DN, Wen W, Xueping E, Klein S, Semenkovich CF, Bae KT, Quirk EK, Powderly WG, Yarasheski KE, & Li E. Alterations in thigh subcutaneous adipose tissue gene expression. Metabolism 54: 561-7 (2005).
Crimmins DL. Human N-terminal proBNP is a monomer. Clin. Chem. 51: 1035-1038 (2005).
Dalla Man C, Yarasheski KE, Caumo A, Robertson H, Toffolo G, Polonsky KS, & Cobelli C. Insulin sensitivity by oral glucose minimal models: Validation against clamp. Am J Physiol Endocrinol Metab. 289: E954-9 (2005).
*Hsu FF & Turk J. Structural studies on phosphatidylserine by tandem quadrupole and multiple stage quadrupole ion-trap mass spectrometry with electrospray ionization. J. Am. Soc. Mass Spectrom. 16: 1510-1522 (2005).
*Hsu FF & Turk J. Mechanisms for phospholipid fragmentation during electrospray ionization mass spectrometry with collision-induced dissociation. In Modern Methods for Lipid Analysis by Liquid Chromatography-Mass Spectrometry and Related Techniques (WC Byrdwell, ed.), pp. 61-179, American Oil Chemists Society Press, Champaign, IL (2005)
*Hsu FF, Turk J, Rhoades ER, Russell DG, Shi Y, & Groisman EA. Structural characterization of cardiolipin by tandem quadrupole and multiple stage quadrupole ion-trap mass spectrometry with electrospray ionization. J. Am. Soc. Mass Spectrom. 16: 491-504 (2005).
Ippolito JE, Xu J, Jain S, Moulder K, Mennerick S, Crowley JR, Townsend RR, & Gordon JI. An integrated functional genomics and metabolomics approach for human neuroendocrine cancers. Proc. Natl. Acad. Sci. 102: 9901-9906 (2005).
Lakshmi VM, Hsu FF, & Zenser TV. Nitric oxide-mediated nitrosation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline potentiated by hemin and myeloperoxidase. Chem Res Toxicol. 18:1038-47 (2005).
*Li YL, Gross ML, & Hsu FF. Ionic liquid matrices for improved analysis of phospholipids by MALDI/TOF mass spectrometry. J. Am. Soc. Mass Spectrom. 16: 679-682 (2005).
Mani SK, Reyna AM, Alejandro MA, Crowley JR, & Markaverich BM. Endocrine disruption by tetrahydrofurandiols. Steroids 70: 750-4 (2005).
Markaverich BM, Crowley JR, Alejandro MA, Shoulars K, Casajuna N, Mani S, Reyna A, & Sharp J. Leukotoxin diols from corn disrupt endocrine cycles and stimulate breast cancer cell proliferation. Environ Health Perspect 113:1698-704 (2005).
Mondy K, Powderly WG, Claxton SA, Yarasheski KE, Royal M, Stoneman JS, Hoffmann ME, & Tebas P. Alendronate, Vitamin D, and calcium for the treatment of osteopenia/osteoporosis associated with HIV infection. J. Acquir. Immune Defic. Syndr. 38: 426-431 (2005).
Moran JM, Buller RML, McHowat J, Turk J, Wohltmann M, Gross RW, & Corbett JA. Genetic and pharmacologic evidence that iPLA2ß regulates virus-induced iNOS expression by macrophages. J. Biol. Chem. 280: 28162-28168 (2005).
Morse GD, Rosenkranz S, Para MF, Segal Y, Difrancesco R, Adams E, Brizz B, Yarasheski KE, & Reichman RC. Amprenavir and efavirenz pharmacokinetics. Antimicrob Agents Chemother. 49:3373-81 (2005).
Sainathan SK, Tu L, Bishnupuri KS, Han M, Li A, Newberry RD, McDonald KG, Crimmins DL, Houchen C, Anant S, & Dieckgraefe BK. PEGylated murine Granulocyte-macrophage colony-stimulating factor: production, purification, and characterization. Protein Expr. Purif. 44: 94-103 (2005).
Schmidt RE, Dorsey DA, Beaudet LN, Parvin CA, Yarasheski KE, Smith SR, Williamson JR, Peterson RG, & Oates PJ. A potent sorbitol dehydrogenase inhibitor exacerbates sympathetic autonomic neuropathy in diabetes. Exp. Neurol. 192:407-19 (2005).
Shoulars K, Rodrigues MA, Crowley J, Turk J, Thompson T, & Markaverich BM. Nuclear type II [3H]estradiol binding sites: A histone H3-H4 complex. J. Steroid Biochem. Molec. Biol. 96: 19-30 (2005).
Spence KL, Zozobrado JC, Patterson BW, & Hamvas A. Substrate utilization and kinetics of surfactant metabolism in evolving bronchopulmonary dysplasia. J. Pediatr. 147:480-5 (2005).
Storer TW, Woodhouse LJ, Sattler F, Singh AB, Schroeder ET, Beck K, Padero M, Mac P, Yarasheski KE, Geurts P, Willemsen A, Harms MK, & Bhasin S. A randomized, placebo-controlled trial of nandrolone decanoate in human immunodeficiency virus-infected men with weight loss. J Clin Endocrinol Metab. 90: 4474-82 (2005).
Wang Z. Ramanadham S, Ma Z, Bao S, Mancuso DJ, Gross RW, & Turk J. Group VIA Phospholipase A2 (iPLA2ß) forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIß expressed in pancreatic islet ß-cells. J. Biol. Chem. 280: 6840-6849 (2005).
Yarasheski KE, Smith WR, & Powderly WG. Reducing plasma HIV RNA improves muscle amino acid metabolism. Am. J. Physiol. Endocrinol. Metab. 288: E278-84 (2005).
Zhang K, Hsu FF, Scot DA, Docampo R, Turk J, & Beverley SM. Salvage and remodeling of host sphingolipids. Molec. Microbiol. 55: 1566-1578 (2005).

2004:

Bao S, Jin C, Zhang S, Turk J, Ma Z, & Ramanadham S. The beta cell calcium-independent Group VIA phospholipase A2 (iPLA2ß). Tracking iPLA2ß movements in response to stimulation with insulin secretagogues in INS-1 cells. Diabetes 53: S186-S189 (2004).
Bao S, Miller DJ, Ma Z, Wohltmann M, Eng G, Ramanadham S, Moley K, & Turk J. Male mice that do not express Group VIA Phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility. J. Biol. Chem. 279: 38194-38200 (2004).
Binder ER, Brown M, Sinacroe DR, Steger-May K, Yarasheski KE, & Schectman KB. Effects of extended outpatient rehabilitation after hip fracture: a randomized controlled trial. J. Am. Med. Assoc. 292: 837-846 (2004).
Brodsky IG, Suzara D, Hornberger TA, Goldspink P, Yarasheski KE, Smith S, Kukowski J, Esser K, & Bedno S. Isoenergetic dietary protein restriction decreases myosin heavy chain IIx fraction and myosin heavy chain production in humans. J. Nutr. 134: 328-334 (2004).
Brown, J., Theisler,C., Silberman, S., Magnuson, D., Marquez-Sterling, N., Yager, D., Crowley, J., Sambamurti, K., Rahman, M.M., Reiss A.B., Eckman, C.B., and Wolozin, B. Differential Expression of Cholesterol Hydroxylases in Alzheimers Disease. J. Biol. Chem. 279: 34674-81 (2004).
Campbell WW, Haub MD, Fluckey JD, Ostlund RE Jr, Thyfault JP, Morse-Carrithers H, Hulver MW, Birge ZK. Pinitol supplementation does not affect insulin-mediated glucose metabolism and muscle insulin receptor content and phosphorylation in older humans. J Nutr. 2004; 134: 2998-3003.
Campbell WW, Joseph LJ, Ostlund RE Jr, Anderson RA, Farrell PA, Evans WJ. Resistive training and chromium picolinate: effects on inositols and liver and kidney functions in older adults. Int J Sport Nutr Exerc Metab. 14:430-42 (2004).
Gerber MT, Mondy KE, Yarasheski KE, Drechsler H, Claxton S, Stoneman J, DeMarco D, Powderly WG, Tebas P. Niacin in HIV-infected individuals with hyperlipidemia receiving potent antiretroviral therapy. Clin Infect Dis. 39:419-25 (2004).
Green PS, Mendez AJ, Jacob JS, Crowley JR, Hyman BT, & Heinecke JW. Neuronal expression of myeloperoxidase is increased in Alzheimer’s disease. J. Neurochem. 90: 724-733 (2004).
Hamvas A, Nogee LM, White FV, Schuler P, Hackett BP, Huddleston CD, Mendeloff EN, Hsu FF, Wert SE, Gonzales LW, Beers MF, & Ballard PL. Progressive lung disease and surfactant dysfunction with deletion of surfactant protein C gene. Am. J. Respir. Cell Mol. Biol. 30: 771-776 (2004).
*Hsu FF, Turk J, Shi Y, & Groisman EA. Characterization of acylphosphatidylglycerols from Salmonella typhimurium by tandem mass spectrometry with electrospray ionization. J. Am. Soc. Mass Spectrom. 15: 1-11 (2004).
*Hsu FF & Turk J. Studies on sulfatides by quadrupole ion-trap mass spectrometry with electrospray ionization. Structural characterization and the fragmentation processes that include an unusual internal galactose residue loss and the classical charge-remote fragmentations. J. Am. Soc. Mass Spectrom. 15: 536-546 (2004).
Lakshmi VM, Hsu FF, & Zenser TV. 2-Nitrosoamino-3-methylimidazo[4,5-f]quinoline stability and reactivity. Chem. Res. Toxicol. 17: 709-16 (2004).
Lee H, Hsu FF, Turk J, & Groisman EA. The PmrA-regulated pmrC gene mediates phosphoethanolamine modification of the lipid A and polymyxin resistance in Salmonella enterica. J. Bacteriol. 2004; 186: 4124-33 (2004).
Lee JT, Xu J, Yang DI, Ku G, Han X, & Hsu CY. Amyloid beta peptides induce cell death through activation of neutral sphingomyelinase-ceramide pathway in oligodendrocytes in culture. J. Cell Biol. 164: 123-131 (2004).
Manary MJ, Yarasheski KE, Berger R & Broadhead RL. Nutritional status affects CO2 production during acute infection in Malawian children. Eur. J. Clin. Nutr. 58; 116-120 (2004).
Manary MJ, Yarasheski KE, Berger R, Smith S, & Broadhead RL. Whole-body leucine kinetics during acute infection in marasmic Malawian children. Pediatr. Res. 55: 940-946 (2004).
Manary MJ, Yarasheski KE, Smith S, Abrams ET, Hart CA. Protein quantity, not protein quality, accelerates whole-body leucine kinetics and the acute-phase response during acute infection in marasmic Malawian children. Br J Nutr. 92: 589-95 (2004).
Nassir F, Xie Y, Patterson BW, Luo J, & Davidson NO. Hepatic excretion of small lipoprotein particles in apobec-1-/- mice is regulated by the LDL receptor. J. Lipid Res. 45: 1649-59 (2004).
Ory DS. Nuclear receptor signaling in the control of cholesterol homeostasis: have the orphans found a home? Circ Res. 2004; 95: 660-70.
Ory DS. The Niemann-Pick disease genes; regulators of cellular cholesterol homeostasis. Trends Cardiovasc Med. 2004; 14: 66-72.
Ostlund RE. Phytosterols and cholesterol metabolism. Curr. Opin. Lipidol. 15: 37-41 (2004).
*Ramanadham S, Hsu FF, Zhang S, Jin C, Bohrer A, Ma Z, & Turk J. Apoptosis of insulin-secreting cells is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2ß) and suppressed by inhibition of iPLA2ß. Biochemistry 43: 918-930 (2004).
Ramanadham S, Song H, Bao S, Hsu FF, Zhang S, Ma Z, Jin C, & Turk J. Islet complex lipid involvement in the actions of Group VIA calcium-independent phospholipase A2 in beta cells. Diabetes 53: S175-S185 (2004).
Schroeder ET, Zheng L, Yarasheski KE, Qian D, Stewart Y, Flores C, Martinez C, Terk M, & Sattler. Treatment with oxandrolone and the durability of effects in older men. J. Appl. Physiol. 96: 1055-62 (2004).
Shanely RA, Van Gammeren D, DeRuisseau KC, Zergoglu AM, McKenzie MJ, Yarasheski KE, & Powers SK. Mechanical ventilatin depresses protein synthesis in the rat diaphragm. Am. J. Respir. Crit. Care Med. 170: 994-999 (2004).
Shi Y, Cromie MJ, Hsu FF, Turk J, & Groisman EA. PhoP regulated Salmonella resistance to the anitmicrobial peptides magainin 2 and polymyxin B. Mol. Microbiol. 2004; 53: 229-241 (2004).
*Song H, Hecimovic S, Goate A, Hsu FF, Bao S, Vidavsky I, Ramanadham S, & Turk J. Characterization of N-terminal processing of Group VIA Phospholipase A2 and of potential cleavage sites of amyloid precursor protein constructs by automated identification of signature peptides in LC/MS/MS analyses of proteolytic digests. J. Am. Soc. Mass Spectrom. 15: 1780-1793 (2004).
Su X, Han X, Yang J, Mancuso J, Bickel PE, & Gross RW. Sequential ordered fatty acid alpha oxidation and delata-9 desaturation are major determinants of lipid storage and utilization in differentiating adipocytes. Biochemistry 43: 5033-44 (2004).
Turk J & Ramanadham S. The expression and function of a Group VIA calcium-independent phospholipase A2 (iPLA2b) in beta cells. Can J. Physiol. Pharmacol. 82: 824-832 (2004).
Zhang J, Dudley-Rucker N, Crowley JR, Lopez-Perez E, Issandou M, Schaffer JE & Ory DS. The steroidal analog GW707 activates the SREBP pathway through disruption of intracellular cholesterol trafficking. J. Lipid Res. 45: 223-31 (2004).

2003:

Acharya U, Patel S, Koundakjian E, Nagashima, Han X, & Acharya JK. Modulation of sphingolipid biosynthetic pathway rescues photoreceptor degeneration. Science 299: 1740-1743 (2003).
Bohlin K, Merchak A, Spence KL, Patterson BW, & Hamvas A. Endogenous surfactant metabolism in newborn infants with and without respiratory failure. Pediatr. Res. 54:185-191 (2003).
Cozzolino M, Vidal M, Aarcidiacono MV, Tebas P, Yarasheski KE, & Dusso AS. HIV protease inhibitors impair vitamind D bioactivation to 1,25-dihydroxyvitamin D. AIDS 17: 513-520 (2003).
Finck BN, Han X, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, & Kelly DA. A critical role for PPARa-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation of phenotype by dietary fat content. Proc. Natl. Acad. Sci. USA 100, 1226-1231 (2003).
Frolov A, Zielinsky SE, Crowley JR, Dudley-Rucker N, Schaffer JE, & Ory DS. NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of LDL cholesterol-derived oxysterols. J. Biol. Chem. 278: 25517-25 (2003).
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